This product is an Anti-Human C7 Polyclonal Antiserum from goats immunized with highly purified human C7 protein. It is not a purified IgG fraction.
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Host Animal | Goats |
Isotype | IgG |
Immunogen | C7 protein |
Applications | Western Blots; ELISA; Immunodiffusion |
Application Notes | Immunodiffusion: 1/16; WB: 16,000; ELISA: 1/32,000 |
Specificity | C7 |
Format | Frozen liquid |
Size | 1ml |
Storage | Store at 4°C short term. Store at -20°C or below long term. Avoid freeze-thaw cycles. |
Target Name | C7 |
Alternative Names | Complement C7; Complement Component 7; Complement Component C7 |
Gene ID | 730 |
UniProt ID | P10643 |
Introduction | Complement component 7 is a protein involved in the complement system of the innate immune system. C7 is part of the membrane attack complex (MAC) which creates a hole on pathogen surfaces, leading to cell lysis and death. Its primary task is to bind the C5bC6 complex together. This junction alters the configuration of the protein molecules, exposing a hydrophobic site on C7 that allows the C7 to insert into the phospholipid bilayer of the pathogen. |