Goat Anti-Mouse Clusterin Polyclonal Antibody(Cat#: CTA-419)

This product is an unconjugated anti-Mouse Clusterin Polyclonal antibody generated from the Goat. The antibody can be used for WB; IHC; IP; ELISA.

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Specifications
Clonality Polyclonal
Host Animal Goat
Isotype IgG
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse Clusterin
Glu22-Glu448
Species Reactivity Mouse
Applications WB; IHC; IP; ELISA
Application Notes WB: 0.1 µg/mL
IHC: 5-15 µg/mL
IP: 25 µg/mL
ELISA (Capture): 0.2-0.8 µg/mL
The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with Mouse Clusterin.
Purity ≥95% as determined by SDS-PAGE
Format Lyophilized
Size 25; 100 µg
Storage 12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Type Primary Antibody
Target
Target Name Clusterin
Alternative Names Cli; ApoJ; Sgp2; SP-40; Sgp-2; Sugp-2; AI893575; D14Ucla3
Gene ID 12759
UniProt ID Q06890
Information
Introduction Clusterin (apolipoprotein J) is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging. CLU is a member of the small heat shock protein family and, thus, a molecular chaperone. Unlike most other chaperone proteins, which aid intracellular proteins, CLU is a Golgi chaperone that facilitates the folding of secreted proteins in an ATP-independent way.


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For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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