This product is an ELISA kit for the determination of Human CD59 in the samples of Plasma, Serum, Tissue Homogenate. It is highly sensitive and available for the detection of Human CD59 as low as 4 ng/ml.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Assay Type | Sandwich ELISA |
Sensitivity | 4 ng/ml (4-3000 ng/ml) |
Pack Size | 96 tests |
Species Reactivity | Human |
Target | CD59 |
Applications | ELISA |
Storage | 4°C for 6 months |
Introduction | CD59 glycoprotein is a potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |