This product is an ELISA kit for the determination of Human Complement C3a des Arg in the samples of serum, plasma or cell culture medium. It is highly sensitive and available for the detection of Human Complement C3a des Arg as low as 0.120 ng/mL.
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Assay Type | Sandwich ELISA |
Sensitivity | 0.120 ng/mL (0.313-20 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Human |
Target | C3a |
Cross Reactivity | C3a des Arg (100%), C3 (1.28%), C4a des Arg (0.40%), C4 (0.31%), C5a des Arg (0.10%), C5 (0.05%) |
Applications | ELISA |
Storage | 4°C |
Introduction | Complement C3A, together with C3B, are proteins released from cleavage of complement C3 protein. C3a is a 77 residue anaphylatoxin that binds to the C3a receptor (C3aR), a class A G protein-coupled receptor. C3 plays an important role in both innate immunity and adaptive immunity by functioning as an effector of the complement system including T cell activation and survival, angiogenesis stimulation,chemotaxis, mast cell degranulation, and macrophage activation. |