Monkey Complement Factor H ELISA Kit(Cat#: CTK-502)
This product is an ELISA kit for the determination of Monkey Complement Factor H in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Monkey Complement Factor H as low as 0.938 ng/mL.
Summary
Customer Reviews
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Specifications
| Assay Type |
Sandwich ELISA |
| Sensitivity |
0.938 ng/mL (1.563-100 ng/mL) |
| Pack Size |
96 tests |
| Species Reactivity |
Monkey |
| Target |
Factor H |
| Cross Reactivity |
No significant cross-reactions have been observed between Monkey Complement Factor H and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications |
ELISA |
| Storage |
4°C |
Information
| Introduction |
Complement factor H plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. For example, interacts with CR3/ITGAM receptor and thereby mediates the adhesion of human neutrophils to different pathogens. In turn, these pathogens are phagocytosed and destroyed. |
Customer Review
The quality of the reagents is excellent
Excellent
The kit is well-designed, with clear instructions and all necessary components included. We achieved consistent, reproducible results across multiple experiments, which is crucial for our ongoing studies.
The kit stands out for its ease of use and reliability
Excellent
The protocol was straightforward, and the results were both accurate and reproducible. It's been particularly useful in our research on complement system abnormalities. The customer service team was also very responsive to our queries, which made the whole process smoother.
Provided clear and consistent results
Excellent
The detailed manual included helpful troubleshooting tips, and the data we obtained has been instrumental in advancing our projects. I would highly recommend this kit to researchers working with primate models.
The assay was straightforward to set up, and we received our results quickly
Excellent
The sensitivity of the kit allowed us to measure Factor H levels accurately even in diluted samples. The kit is well-organized, and the results were obtained with minimal effort.
So far, we are quite pleased
Excellent
The kit was easy to use, and the results were reproducible across multiple experiments. The pre-coated plates saved a lot of time, and the standard curve was very reliable.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
