This product is an ELISA kit for the determination of Mouse Adiponectin in the samples of Serum, Plasma, Cell Culture Supernatant, Tissue Homogenate, Cell Lysate. It is highly sensitive and available for the detection of Mouse Adiponectin as low as 0.039 ng/mL.
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Assay Type | Sandwich ELISA |
Sensitivity | 0.039 ng/mL (0.156-10 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Mouse |
Target | Adiponectin |
Cross Reactivity | No significant cross-reactions have been observed between Mouse Adiponectin and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | Short-term storage at 4°C and long-term storage at -20°C. |
Introduction | Adiponectin is an important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |