Mouse Anti-Human CD59 Monoclonal Antibody (CTJS-154) [iFluor® 546](Cat#: CTA-719)
This product is a conjugated anti-Human MAC-inhibitory protein (CD59) Monoclonal antibody (CTJS-154) generated from the Mouse. The antibody can be used for WB, IF, IHC, FC.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-154 |
| Host Animal |
Mouse |
| Isotype |
IgG1 κ |
| Epitope |
SCR4 domain |
| Immunogen |
Recombinant human CD59, a.a. 26-110 |
| Species Reactivity |
Human; Mouse; rat |
| Applications |
WB; IF; IHC; FC |
| Application Notes |
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human, Mouse, and Rat MAC-inhibitory protein (CD59). |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
iFluor® 546 |
| Format |
Liquid |
| Size |
200 µg |
| Storage |
Store in dark at 4°C. Do Not Freeze. |
| Type |
Primary Antibody |
Target
| Target Name |
CD59 |
| Alternative Names |
CD59 Molecule; CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; 20 KDa Homologous Restriction Factor; Membrane Inhibitor Of Reactive Lysis; CD59 Glycoprotein; MEM43 Antigen; MAC-IP; CD59; MAC-Inhibitory Protein; CD59 Antigen, Complement Regulatory Protein; MAC-Inhibitory Protein; Protectin |
| Gene ID |
966 |
| UniProt ID |
P13987 |
Information
| Introduction |
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
