Mouse Anti-Human CFHR5 Monoclonal Antibody (CTJS-159)(Cat#: CTA-167)

This product is an unconjugated anti-Human CFHR5 Monoclonal antibody (CTJS-159) generated from the Mouse. The antibody can be used for WB; ELISA; FC; IF; IHC.

INQUIRY Datasheet MSDS COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number

Summary Related Products & Services


Specifications
Clonality Monoclonal
Clone CTJS-159
Host Animal Mouse
Isotype IgG2a
Immunogen Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. Coli.
Species Reactivity Human
Applications WB; ELISA; FC; IF; IHC
Application Notes WB: 1:500-1:2000
ELISA: 1:10000
FC: 1:200-1:400
IF: 1:200-1:1000
IHC: 1:200-1:1000
The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with Human CFHR5.
Purity ≥95% as determined by SDS-PAGE
Format Liquid
Size 25; 100 µg
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Type Primary Antibody
Target
Target Name CFHR5
Alternative Names Complement Factor H Related 5; CFHL5; FHR-5; FHR5; Complement Factor H-Related Protein 5; Complement Factor H-Related 5; Factor H-Related Protein 5; Factor H Related Protein 5; CFHR5D
Gene ID 81494
UniProt ID Q9BXR6
Information
Introduction Complement factor H-related protein 5 is a protein that in humans is encoded by the CFHR5 gene. CFHR5 is structurally related to complement factor H which plays an important role in the regulation of a branch of the innate immune system called the alternative complement pathway. Like complement factor H, CFHR5 is able to bind to complement C3. A mutation in CHFR5 was found in patients with the disease CFHR5 nephropathy, which is a common cause of renal disease in Cyprus. The mutated form of the protein found in patients with this disease has impaired ability to bind to complement C3, suggesting that CFHR5 is important in protecting the kidneys from attack by the complement system.


Related Products & Services

Related Products
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
Online Inquiry
×