Mouse Anti-Human Clusterin Monoclonal Antibody (CTJS-48)(Cat#: CTA-732)

Name: Mouse Anti-Human Clusterin Monoclonal Antibody (CTJS-48)
SKU: CTA-732
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human Clusterin Monoclonal antibody (CTJS-48) generated from the Mouse. The antibody can be used for WB, IP, IF, IHC, ELISA.

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Specifications

Clonality	Monoclonal
Clone	CTJS-48
Host Animal	Mouse
Isotype	IgG2a κ
Immunogen	Recombinant human Clusterin, a.a. 120-449
Species Reactivity	Human
Applications	WB; IP; IF; IHC; ELISA
Application Notes	WB: 1:100-1:1000 IF: 1:50-1:500 IHC: 1:50-1:500 ELISA: 1:30-1:3000 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human Clusterin.
Purity	≥95% as determined by SDS-PAGE
Conjugation	Unconjugated
Format	Liquid
Size	200 µg
Storage	Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle.
Type	Primary Antibody

Target

Target Name	Clusterin
Alternative Names	Clusterin; Testosterone-Repressed Prostate Message; Sulfated Glycoprotein; Apolipoprotein J; TRPM-2; Complement Cytolysis Inhibitor; Complement Lysis Inhibitor; Ku70-Binding Protein 1; SP-40; APOJ; CLU1; CLU2; Aging-Associated Protein 4; APO-J; TRPM2; Apo-J 4; CLU
Gene ID	1191
UniProt ID	P10909

Information

Introduction

Clusterin is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. It is a member of the small heat shock protein family and, thus, a molecular chaperone. Unlike most other chaperone proteins, which aid intracellular proteins, CLU is a Golgi chaperone that facilitates the folding of secreted proteins in an ATP-independent way. The gene is highly conserved in species, and the protein is widely distributed in many tissues and organs, where it participates in a number of biological processes, including lipid transport, membrane recycling, cell adhesion, programmed cell death, and complement-mediated cell lysis.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.