This product is an unconjugated anti-Human Clusterin Monoclonal antibody (CTJS-865) generated from the Mouse. The antibody can be used for WB; IF; IHC; IP.
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Clonality | Monoclonal |
Clone | CTJS-865 |
Host Animal | Mouse |
Isotype | IgG1 |
Immunogen | Purified human clusterin (TRPM-2) |
Species Reactivity | Human |
Applications | WB; IF; IHC; IP |
Application Notes | WB: 1:2000 IF: 1:10-1:500 IHC: 1:10-1:500 IHC: -Frozen 1:10-1:500 IHC: -Paraffin 1:10-1:500 IP: 1:10-1:500 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human Clusterin. |
Purity | ≥95% as determined by SDS-PAGE |
Format | Liquid |
Size | 25; 100 µg |
Storage | 4°C |
Type | Primary Antibody |
Target Name | Clusterin |
Alternative Names | Testosterone-Repressed Prostate Message; Clusterin (Complement Lysis Inhibitor, SP-40, 40, Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2, Apolipoprotein J); Apolipoprotein J; Complement-Associated Protein SP-40, 40; Complement Cytolysis Inhibitor; Complement Lysis Inhibitor; Sulfated Glycoprotein 2; Ku70-Binding Protein 1; NA1/NA2; TRPM-2; APOJ; KUB1; CLI; Aging-Associated Gene 4 Protein; Aging-Associated Protein 4; APO-J; SGP-2; SP-40; TRPM2; Apo-J; AAG4; CLU1; CLU2; SGP2 |
Gene ID | 1191 |
UniProt ID | P10909 |
Introduction | Clusterin is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. It is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, Clusterin is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging. |