This product is an unconjugated anti-Human Complement Clusterin Monoclonal antibody (TJL-130) generated from the Mouse. The antibody can be used for WB, IHC, IP.
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Clonality | Monoclonal |
Clone | TJL-130 |
Host Animal | Mouse |
Isotype | IgG2b |
Immunogen | Recombinant Human Clusterin |
Species Reactivity | Human |
Applications | WB; IHC; IP |
Application Notes | IHC: 5-25 ug/mL IP: 25 ug/mL WB: 2 ug/mL |
Specificity | This antibody reacts with Human Complement Clusterin. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | Unconjugated |
Format | Liquid |
Size | 100 ug |
Storage | Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
Type | Primary Antibody |
Target Name | Clusterin |
Alternative Names | Clusterin; Testosterone-Repressed Prostate Message; Sulfated Glycoprotein; Apolipoprotein J; TRPM-2; Complement Cytolysis Inhibitor; Complement Lysis Inhibitor; Ku70-Binding Protein 1; SP-40; APOJ; CLU1; CLU2; Aging-Associated Protein 4; APO-J; TRPM2; Apo-J 4; CLU |
Gene ID | 1191 |
UniProt ID | P10909 |
Introduction | Clusterin is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. It is a member of the small heat shock protein family and, thus, a molecular chaperone. Unlike most other chaperone proteins, which aid intracellular proteins, CLU is a Golgi chaperone that facilitates the folding of secreted proteins in an ATP-independent way. The gene is highly conserved in species, and the protein is widely distributed in many tissues and organs, where it participates in a number of biological processes, including lipid transport, membrane recycling, cell adhesion, programmed cell death, and complement-mediated cell lysis. |