Mouse Anti-Human Ficolin-2 Monoclonal Antibody (TJL-227) [DyLight 488](Cat#: CTMM-0322-JL2345)

This product is a DyLight 488 conjugated anti-Human Complement Ficolin-2 Monoclonal antibody (TJL-227) generated from the Mouse. The antibody can be used for WB, ELISA.

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Specifications
Clonality Monoclonal
Clone TJL-227
Host Animal Mouse
Isotype IgG2a Kappa
Immunogen Recombinant Human Ficolin-2 and full-length L-Ficolin (Ficolin-2) protein
Species Reactivity Human
Applications WB; ELISA
Application Notes The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with Human Complement Ficolin-2.
Purity ≥95% as determined by SDS-PAGE
Conjugation DyLight 488
Format Liquid
Size 0.1 ml
Storage Store in dark at 4°C. Do Not Freeze.
Type Primary Antibody
Target
Target Name Ficolin-2
Alternative Names Ficolin; Collagen/Fibrinogen Domain-Containing Protein 2; Serum Lectin P35; L-Ficolin; 37 KDa Elastin-Binding Protein; Ficolin-Beta; Ficolin-2; Ficolin B; Hucolin; EBP-37; FCNL; Ficolin (Collagen/Fibrinogen Domain Containing Lectin) 2 (Hucolin); Ficolin-B; P35
Gene ID 2220
UniProt ID Q15485
Information
Introduction Ficolin-2 is a protein that in humans is encoded by the FCN2 gene, which is initially identified as L-ficolin. L-Ficolin is an innate immunity pattern recognition molecule found in human serum. It binds to distinct pathogen-associated molecular patterns (PAMP) such as carbohydRates (GlcNAc), lipoteichoic acid and acetylated groups, thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP (MBL-associated serine protease).


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For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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