This product is an ELISA kit for the determination of Mouse Complement C5aR1 in the samples of Cell Lysate, Tissue Homogenate. It is highly sensitive and available for the detection of Mouse Complement C5aR1 as low as 0.124 ng/mL.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Assay Type | Sandwich ELISA |
Sensitivity | 0.124 ng/mL (0.312-20 ng/mL) |
Pack Size | 96 tests |
Species Reactivity | Mouse |
Target | C5aR1 |
Cross Reactivity | No significant cross-reactions have been observed between Mouse Complement C5aR1 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | 4°C |
Introduction | C5a anaphylatoxin chemotactic receptor 1 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |