This product is a 93 kDa native human Factor B protein isolated from normal human serum. It is availible for Functional Assays, ELISA.
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Specie Reactivity | Human |
Target | Factor B |
Molecule Mass | 93 kDa |
Purity | >95% determined by SDS-PAGE |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | 10 mM sodium phosphate, 145 mM NaCl, pH 7.2 |
Applications | Functional Assays; ELISA |
Product Form | Frozen liquid |
Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Introduction | Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |
Alternative Names | Complement Factor B; B-Factor, Properdin; Properdin Factor B; Glycine-Rich Beta-Glycoprotein; Glycine-Rich Beta Glycoprotein; C3 Proaccelerator; C3 Proactivator; CFB; FB |
Gene ID | 629 |
UniProt ID | P00751 |
I highly recommend this productExcellentThe protein we received was of exceptional quality. It exhibited high purity and stability, which significantly improved our ELISA results. The reproducibility of our assays has never been better. We were also pleased with the fast shipping and excellent customer support.
We plan to continue using this product for future experimentsExcellentWe recently switched to this protein for our functional assays, and the difference is night and day. The protein's high activity and stability have enhanced the sensitivity of our tests. Customer service was also very helpful with our technical queries.
Highly pure and stableExcellentWe chose this protein for our complement pathway experiments and were not disappointed. The protein showed high activity and consistency, which enhanced the accuracy of our ELISA tests.
We are very satisfied with this productExcellentThe protein has been a reliable reagent in our laboratory. Its performance in ELISA and functional assays has been consistently high, allowing us to generate accurate and reproducible data. We are very satisfied with this product.