Rabbit Anti-Human CD46 Monoclonal Antibody (CTJS-195)(Cat#: CTA-251)
This product is an unconjugated anti-Human CD46 Monoclonal antibody (CTJS-195) generated from the Rabbit. The antibody can be used for WB; IF; IHC.
Summary
Related Products & Services
Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-195 |
| Host Animal |
Rabbit |
| Isotype |
IgG |
| Immunogen |
Synthetic peptide within human CD46 aa 50-100 |
| Species Reactivity |
Human; Rat |
| Applications |
WB; IF; IHC |
| Application Notes |
WB: 1:100-1:2000
IF: 1:10 - 1:500
IHC: 1:10 - 1:500
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human, Rat CD46. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
100 µL |
| Storage |
Store at 4°C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
CD46 |
| Alternative Names |
AHUS2; CD46 antigen; CD46 molecule complement regulatory protein; CD46; MCP; membrane cofactor protein (CD46; trophoblast-lymphocyte cross-reactive antigen); MIC10; TLXcomplement regulatory protein; Trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen |
| Gene ID |
4179 |
| UniProt ID |
P15529 |
Information
| Introduction |
CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. CD46 is an inhibitory complement receptor. The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation (through cleavage) of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. The protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
