This product is a conjugated anti-Human C5aR1 Monoclonal antibody (CTJS-544) generated from the Rat. The antibody can be used for FC.
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Clonality | Monoclonal |
Clone | CTJS-544 |
Host Animal | Rat |
Isotype | IgG2a |
Immunogen | RBL-2H3 transfected cells expressing human C5aR |
Species Reactivity | Human |
Applications | FC |
Application Notes | FC: 1 µg/10^6 cells The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human C5aR1. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | Biotin |
Format | Liquid |
Size | 100 μg |
Storage | Store in dark at 4°C. Do Not Freeze. |
Type | Primary Antibody |
Target Name | C5aR1 |
Alternative Names | Complement C5a Receptor 1; C5AR; C5a Anaphylatoxin Chemotactic Receptor 1; Complement Component 5a Receptor 1; C5a-R; C5R1; CD88; Complement Component 5 Receptor 1 (C5a Ligand); C5a Anaphylatoxin Chemotactic Receptor 4; Complement Component 5 Receptor 1; C5a Anaphylatoxin Receptor; CD88 Antigen; C5AR1; C5aR |
Gene ID | 728 |
UniProt ID | P21730 |
Introduction | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. |