This product is an ELISA kit for the determination of Rat Complement C4bpb in the samples of Serum, Plasma, Tissue Homogenate. It is highly sensitive and available for the detection of Rat Complement C4bpb as low as 125 ng/mL.
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Assay Type | Sandwich ELISA |
Sensitivity | 125 ng/mL |
Pack Size | 96 tests |
Species Reactivity | Rat |
Target | C4BPB |
Cross Reactivity | No significant cross-reactions have been observed between Rat Complement C4bpb and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications | ELISA |
Storage | Short-term storage at 4°C and long-term storage at -20°C. |
Introduction | C4b-binding protein beta chain controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S. |