Recombinant Cynomolgus monkey CD59 Protein-N-terminal His Tag(Cat#: CTP-345)
This product is a recombinant Cynomolgus monkey CD59 protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for WB, ELISA, IP.
Summary
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Specifications
| Expressed Host |
E.coli |
| Specie Reactivity |
Cynomolgus monkey |
| Target |
CD59 |
| Purity |
>95 % determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 |
| Applications |
WB; ELISA; IP |
| Product Form |
Lyophilized |
| Storage |
Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Protein Information
| Introduction |
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. |
| Alternative Names |
CD59 Molecule; CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; 20 KDa Homologous Restriction Factor; Membrane Inhibitor Of Reactive Lysis; CD59 Glycoprotein; MEM43 Antigen; MAC-IP; CD59; MAC-Inhibitory Protein; CD59 Antigen, Complement Regulatory Protein; MAC-Inhibitory Protein; Protectin |
| Gene ID |
101867071 |
| UniProt ID |
Q8SQ46 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
