Recombinant Human C4BPB Protein-His tag(Cat#: CTP-071)
This product is a 29 kDa recombinant human C4BPB protein with a N-Terminal His-tag expressed in the E. coli.
Summary
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Specifications
| Expressed Host |
E. Coli |
| Specie Reactivity |
Human |
| Target |
C4BPB |
| Molecule Mass |
29 kDa |
| Purity |
>90% by SDS-PAGE |
| Formulation |
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15M NaCl |
| Product Form |
Liquid |
| Storage |
Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
Protein Information
| Introduction |
C4b-binding protein beta chain controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S. |
| Alternative Names |
C4b binding protein beta chain; C4b-binding protein beta chain, C4BP; Complement component 4 binding protein, beta chain; Complement component 4-binding protein, beta |
| Gene ID |
725 |
| UniProt ID |
P20851 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
