This product is a 80.52 kDa recombinant human Complement 1 Inhibitor with a GST-tag at N-terminal expressed in the Wheat Germ (in vitro). It is available for ELISA, WB, PA, AP.
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Expressed Host | Wheat Germ (in vitro) |
Specie Reactivity | Human |
Target | C1 Inhibitor |
Molecule Mass | 80.52 kDa |
Purity | >90% by SDS-PAGE and HPLC analyses |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 |
Applications | ELISA; WB; PA; AP |
Product Form | Liquid |
Storage | Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
Introduction | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
Alternative Names | Plasma protease C1 inhibitor; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1; C1IN; C1NH; HAE1; HAE2; C1INH |
Gene ID | 710 |
UniProt ID | P05155 |