Recombinant Mouse C1s1 Protein-Polyhistidine tag(Cat#: CTP-030)
This product is a 76.6 kDa recombinant mouse C1S1 protein with a polyhistidine tag at the C-terminus expressed in the HEK293 Cells.
Summary
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Specifications
| Expressed Host |
HEK293 Cells |
| Specie Reactivity |
Mouse |
| Target |
C1SA |
| Molecule Mass |
76.6 kDa |
| Purity |
>85 % as determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
PBS, pH 7.4 |
| Product Form |
Lyophilized |
| Storage |
Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Protein Information
| Introduction |
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4 . It cleaves of Arg-|-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-|-Lys bond in complement component C2 to form C2a and C2b: the 'classical' pathway C3 convertase. |
| Alternative Names |
Complement C1s-A subcomponent; C1 esterase; Complement component 1 subcomponent s-A |
| Gene ID |
50908 |
| UniProt ID |
Q8CG14 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
