This product is a 62.3 kDa recombinant rat C4bpa protein with a N-terminal tag or C-terminal tag expressed in the E. Coli or Yeast or Baculovirus or Mammalian Cell.
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Expressed Host | E. Coli or Yeast or Baculovirus or Mammalian Cell |
Specie Reactivity | Rat |
Target | C4BPA |
Molecule Mass | 62.3 kDa |
Purity | >85% (SDS-PAGE) (lot specific) |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | Tris-based buffer, 50% glycerol |
Product Form | Liquid containing glycerol |
Storage | Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
Introduction | C4b-binding protein alpha chain controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component. |
Alternative Names | C4b-binding protein alpha chain; C4bp |
Gene ID | 24235 |
UniProt ID | Q63514 |