This product is a recombinant rat Clusterin protein with a N-terminal 6XHis tag tag expressed in the Yeast. It is availible for WB, ELISA.
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Expressed Host | Yeast |
Specie Reactivity | Rat |
Target | Clusterin |
Purity | >85 % determined by SDS-PAGE |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | Tris-base, 50% glycerol |
Applications | WB; ELISA |
Product Form | Liquid |
Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Introduction | Clusterin is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. It is a member of the small heat shock protein family and, thus, a molecular chaperone. Unlike most other chaperone proteins, which aid intracellular proteins, CLU is a Golgi chaperone that facilitates the folding of secreted proteins in an ATP-independent way. The gene is highly conserved in species, and the protein is widely distributed in many tissues and organs, where it participates in a number of biological processes, including lipid transport, membrane recycling, cell adhesion, programmed cell death, and complement-mediated cell lysis. |
Alternative Names | Clusterin; Testosterone-Repressed Prostate Message; Sulfated Glycoprotein; Apolipoprotein J; TRPM-2; Complement Cytolysis Inhibitor; Complement Lysis Inhibitor; Ku70-Binding Protein 1; SP-40; APOJ; CLU1; CLU2; Aging-Associated Protein 4; APO-J; TRPM2; Apo-J 4; CLU |
Gene ID | 24854 |
UniProt ID | P05371 |