This product is a recombinant rat C1S protein with a N-terminal 6XHis tag tag expressed in the Yeast. It is availible for WB, ELISA.
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Expressed Host | Yeast |
Specie Reactivity | Rat |
Target | C1S |
Purity | >85 % determined by SDS-PAGE |
Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
Formulation | Tris-based buffer,50% glycerol |
Applications | WB; ELISA |
Product Form | Liquid |
Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Introduction | C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. It cleaves the Arg-|-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-|-Lys bond in complement component C2 to form C2a and C2b: the 'classical' pathway C3 convertase. |
Alternative Names | Complement C1s; Complement Component 1, S Subcomponent; Complement Component 1 Subcomponent S; Complement C1s Subcomponent; C1 Esterase; Basic Proline-Rich Peptide IB-1; C1S |
Gene ID | 192262 |
UniProt ID | Q6P6T1 |