shRNA Adenovirus Serotype 5 (ΔE1/E3), pH1-(MICALCL-shRNA-Seq2)(CAT#: AdV-SI0586WQ)
This product is a MICALCL-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The MICALCL gene may cooperate with MAPK1/ERK2 via an intracellular signal transduction pathway in the morphogenetic development of round spermatids to spermatozoa and act as Rab effector protein and play a role in vesicle trafficking. The expression of MICALCL-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
---|---|
Family | Adenoviridae |
Species | Adenovirus |
Serotype | HAdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Insert | MICALCL-shRNA-Seq2 |
Related Target/Protein | MICALCL |
Region | CDS |
TargetSeq | CAAAGCAGACTGGAGCAGAAA |
NCBI RefSeq | NM_032867 |
Alternative Names | Ebitein1 |
Titer | >1*10^10 GC/mL |
Related Diseases | Renal cancer |