shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(KHDRBS1-shRNA-Seq4)(CAT#: AdV-SI0047WQ)

This product is a KHDRBS1-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted.The KHDRBS1 encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. The expression of KHDRBS1-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype HAdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Insert KHDRBS1-shRNA-Seq4
Related Target/Protein KHDRBS1
Region CDS
TargetSeq CCACAAGGGAATACAATCAAA
NCBI RefSeq NM_006559
Alternative Names p62; p68; Sam68
Titer >1*10^10 GC/mL
Related Diseases Primary ovarian insufficiency
Target Gene
Gene ID 10657
Uniprot ID Q07666

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