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Magic™ Membrane Protein Human ADRA1B (Adrenoceptor alpha 1B) Full Length (CAT#: MPC0026K) Made to Order

Datasheet
This product is a 56.8 kDa Human ADRA1B membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADRA1B
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 56.8 kDa
  • TMD
  • 7
  • Sequence
  • MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGL
    VLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLP
    FSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYS
    LQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEE
    PFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKE
    LTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
    GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPC
    SSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERS
    QSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAFPEWKAP
    GALLSLPAPEPPGRRGRHDSGPLFTFKLLTEPESPGTDGGASNGGCEAAA
    DVANGQPGFKSNMPLAPGQF

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ADRA1B
  • Full Name
  • Adrenoceptor alpha 1B
  • Introduction
  • Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
  • Alternative Names
  • ADRA1; ALPHA1BAR; adrenergic, alpha-1B-, receptor; alpha-1B adrenoceptor; alpha-1B adrenoreceptor; ADRA1B; Adrenoceptor alpha 1B

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