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Magic™ Membrane Protein Human CRHR2 (Corticotropin releasing hormone receptor 2) Full Length (CAT#: MPC0070K) Made to Order

This product is a 47.6 kDa Human CRHR2 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CRHR2
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 47.6 kDa
  • TMD
  • 7
  • Sequence
  • MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTC
    WPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEP
    ILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNV
    IHWNLITTFILRNVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNFF
    WMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYE
    NEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
    ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSF
    QGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRI
    SFHSIKQTAAV

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • MBP and 8xHis tag at C-terminal
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CRHR2
  • Full Name
  • Corticotropin releasing hormone receptor 2
  • Introduction
  • The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
  • Alternative Names
  • CRF2; CRFR2; CRF-RB; HM-CRF; CRH receptor 2 variant B; CRH-R2; CRHR2; Corticotropin releasing hormone receptor 2

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