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Magic™ Membrane Protein Human LMTK2 (Lemur tyrosine kinase 2) Full Length (CAT#: MPC1899K) Made to Order

Datasheet
This product is a 164.9 kDa Human LMTK2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LMTK2
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • Molecular Weight
  • 164.9 kDa
  • TMD
  • 2
  • Sequence
  • MPGPPALRRRLLLLLLVLLIAGSAGAAPLPQTGAGEAPPAAEVSSSFVIL
    CVCSLIILIVLIANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQ
    SPAEVFTLSVPNISLPAPSQFQPSVEGLKSQVARHSLNYIQEIGNGWFGK
    VLLGEIYTGTSVARVIVKELKASANPKEQDTFLKNGEPYYILQHPNILQC
    VGQCVEAIPYLLVFEFCDLGDLKAYLRSEQEHMRGDSQTMLLQRMACEVA
    AGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDD
    KKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFDNAAQPY
    SNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWLSPEKRPAA
    EDVHRLLTYLRLQSQRDSEVDFEQQWNALKPNTNSRDSSNNAAFPILDHF
    ARDRLGREMEEVLTVTETSQGLSFEYVWEAAKHDHFDERSRGHLDEGLSY
    TSIFYPVEVFESSLSDPGPGKQDDSGQDVPLRVPGVVPVFDAHNLSVGSD
    YYIQLEEKSGSNLELDYPPALLTTDMDNPERTGPELSQLTALRSVELEES
    STDEDFFQSSTDPKDSSLPGDLHVTSGPESPFNNIFNDVDKSEDLPSHQK
    IFDLMELNGVQADFKPATLSSSLDNPKESVITGHFEKEKPRKIFDSEPLC
    LSDNLMHQDNFDPLNVQELSENFLFLQEKNLLKGSLSSKEHINDLQTELK
    NAGFTEAMLETSCRNSLDTELQFAENKPGLSLLQENVSTKGDDTDVMLTG
    DTLSTSLQSSPEVQVPPTSFETEETPRRVPPDSLPTQGETQPTCLDVIVP
    EDCLHQDISPDAVTVPVEILSTDARTHSLDNRSQDSPGESEETLRLTESD
    SVLADDILASRVSVGSSLPELGQELHNKPFSEDHHSHRRLEKNLEAVETL
    NQLNSKDAAKEAGLVSALSSDSTSQDSLLEDSLSAPFPASEPSLETPDSL
    ESVDVHEALLDSLGSHTPQKLVPPDKPADSGYETENLESPEWTLHPAPEG
    TADSEPATTGDGGHSGLPPNPVIVISDAGDGHRGTEVTPETFTAGSQGSY
    RDSAYFSDNDSEPEKRSEEVPGTSPSALVLVQEQPLPEPVLPEQSPAAQD
    SCLEARKSQPDESCLSALHNSSDLELRATPEPAQTGVPQQVHPTEDEASS
    PWSVLNAELSSGDDFETQDDRPCTLASTGTNTNELLAYTNSALDKSLSSH
    SEGPKLKEPDIEGKYLGKLGVSGMLDLSEDGMDADEEDENSDDSDEDLRA
    FNLHSLSSESEDETEHPVPIILSNEDGRHLRSLLKPTAANAPDPLPEDWK
    KEKKAVTFFDDVTVYLFDQETPTKELGPCGGEACGPDLSGPAPASGSPYL
    SRCINSESSTDEEGGGFEWDDDFSPDPFMSKTTSNLLSSKPSLQTSKYFS
    PPPPARSTEQSWPHSAPYSRFSISPANIASFSLTHLTDSDIEQGGSSEDG
    EKD

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • LMTK2
  • Full Name
  • Lemur tyrosine kinase 2
  • Introduction
  • The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis.
  • Alternative Names
  • LMTK2; BREK; KPI2; LMR2; cprk; KPI-2; hBREK; AATYK2; PPP1R100; serine/threonine-protein kinase LMTK2; CDK5/p35-regulated kinase; apoptosis-associated tyrosine kinase 2; brain-enriched kinase; cyclin-dependent kinase 5/p35-regulated kinase; kinase/phosphatase/inhibitor 2; protein phosphatase 1, regulatory subunit 100; serine/threonine-protein kinase KPI-2; Lemur tyrosine kinase 2

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