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Magic™ Membrane Protein Human LRRN2 (Leucine rich repeat neuronal 2) Expressed in CHO for Antibody Discovery, Partial (19-630aa) (CAT#: MPX0693K)

Datasheet
This product is a 69 kDa Human LRRN2 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LRRN2
  • Protein Length
  • Partial (19-630aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 69 kDa
  • TMD
  • 1
  • Sequence
  • AVPVVPWHVPCPPQCACQIRPWYTPRSSYREA
    TTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDL
    SQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNH
    NQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNK
    VDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLA
    RVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS
    IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSAL
    HQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEP
    PDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMVLHCRALAE
    PEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAGLYTCVAQ
    NLVGADTKTVSVVVGRALLQPGRDEGQGLELRVQETHPYHILLSWVTPPN
    TVSTNLTWSSASSLRGQGATALARLPRGTHSYNITRLLQATEYWACLQVA
    FADAHTQLACVWARTKEATSCHRALGDRPG

Product Description

  • Activity
  • Yes
  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 500 μg/mL in PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • LRRN2
  • Full Name
  • Leucine rich repeat neuronal 2
  • Introduction
  • The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
  • Alternative Names
  • LRRN2; GAC1; LRRN5; LRANK1; FIGLER7; leucine-rich repeat neuronal protein 2; fibronectin type III, immunoglobulin and leucine rich repeat domain 7; glioma amplified on chromosome 1 protein; leucine rich and ankyrin repeats 1; leucine rich repeat neuronal 5; leucine-rich repeat neuronal protein 5; Leucine rich repeat neuronal 2

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