COMP

COMP (Cartilage Oligomeric Matrix Protein) is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-1412Lsx Recombinant COMP Protein (Gln 21-Ala 757) [His] HEK293 Cells. Human COMP, His tag, is expressed in HEK 293 cells. (Uniprot ID: AAI25093) COMP Tumor Antigens Datasheet 100 µg Inquiry

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