CTLA4
CTLA4 is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses. CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. CTLA4 is a member of the immunoglobulin superfamily that is expressed by activated T cells and transmits an inhibitory signal to T cells. CTLA4 is homologous to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-1434Lsx | Recombinant CTLA-4 Protein (Glu 36-Phe 162) [His] | HEK293 Cells. | Mouse CTLA-4 (CD152), His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_033973) | CTLA4 | Tumor Antigens |  |
200 µg | Inquiry |
| VAng-1435Lsx | Recombinant CTLA-4 Protein (Ile 38-Asp 161) [Fc] | HEK293 Cells. | Rat CTLA-4 (CD152), human IgG1 Fc tag, is expressed in HEK 293 cells. (Uniprot ID: Q62859) | CTLA4 | Tumor Antigens | |
100 µg | Inquiry |
| VAng-1436Lsx | Recombinant CTLA-4 Protein (Lys 36-Asp 161) [Fc] | HEK293 Cells. | Rabbit CTLA-4 (CD152), human IgG1 Fc tag, is expressed in HEK 293 cells. (Uniprot ID: P42072) | CTLA4 | Tumor Antigens | |
100 µg | Inquiry |
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
