EGFRvIII
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. Aberrant EGFRvIII signaling has been shown to be important in driving tumor progression and often correlates with poor prognosis.CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
---|---|---|---|---|---|---|---|---|
VAng-1486Lsx | Recombinant EGFRvIII Protein (Leu 25-Ser 645) [Avi] | HEK293 Cells. | Biotinylated Human EGFRvIII, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_005219.2) | EGFRvIII | Tumor Antigens | ![]() |
25 µg | Inquiry |
VAng-1487Lsx | Recombinant EGFRvIII Protein (Leu 25-Ser 645) [His] | HEK293 Cells. | Human EGFRvIII, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_005219.2) | EGFRvIII | Tumor Antigens | ![]() |
50 µg | Inquiry |
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.