GITRL
GITRL is a protein that in humans is encoded by GITRL gene. GITR is a member of the tumor necrosis factor receptor (TNF-R) superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25+/CD4+ regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3844 | Recombinant GITRL Protein (Glu74-Ser199) [His] | Mammalian cells | Recombinant GITRL Protein (Glu74-Ser199) fused with a His tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 13.97 kDa. (Uniprot ID: Q9UNG2) | GITRL | Tumor Antigens |  |
100 µg | Inquiry |
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