GLP1R
GLP1R is a receptor protein found on beta cells of the pancreas. It is involved in the control of blood sugar level by enhancing insulin secretion. It is a member of the glucagon receptor family of G protein-coupled receptors. GLP1R is composed of two domains, one extracellular (ECD) that binds the C-terminal helix of GLP-1, and one transmembrane (TMD) domain that binds the N-terminal region of GLP-1. In the TMD domain there is fulcrum of polar residues that regulates the biased signaling of the receptor while the transmembrane helical boundaries and extracellular surface are a trigger for biased agonism.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3779 | Recombinant GLP1R Protein (Arg24-Tyr145) [His] | Mammalian cells | Recombinant GLP1R Protein (Arg24-Tyr145) fused with a His tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 45-66 kDa. (Uniprot ID: P43220) | GLP1R | Tumor Antigens |  |
100 µg | Inquiry |
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