IDO
IDO is a heme-containing enzyme that in humans is encoded by IDO gene. It is one of three enzymes that catalyze the first and rate-limiting step in the kynurenine pathway, the O2-dependent oxidation of L-tryptophan to N-formylkynurenine, the others being IDO2 and tryptophan 2,3-dioxygenase (TDO). IDO has been implicated in immune modulation through its ability to limit T-cell function and engage mechanisms of immune tolerance. Emerging evidence suggests that IDO becomes activated during tumor development, helping malignant cells escape eradication by the immune system.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3825 | Recombinant IDO Protein (Ala2-Gly403) [His] | Mammalian cells | Recombinant IDO Protein (Ala2-Gly403) fused with a His tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 44 kDa. (Uniprot ID: P14902) | IDO | Tumor Antigens |  |
100 µg | Inquiry |
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