IKZF3
IKZF3 is a protein that in humans is encoded by IKZF3 gene. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3792 | Recombinant IKZF3 Protein (Met1-Lys509) [MYC/DDK] | Mammalian cells | Recombinant IKZF3 Protein (Met1-Lys509) fused with a MYC/DDK tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 55.99 kDa. (Uniprot ID: Q9UKT9) | IKZF3 | Tumor Antigens |  |
100 µg | Inquiry |
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