IL4R

IL4R is a type I cytokine receptor. IL4R encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. Among T cells, the encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitis, asthma, or eczema.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-Cr3789 Recombinant IL4R Protein (Met1-His232) [His] Mammalian cells Recombinant IL4R Protein (Met1-His232) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 43-48 kDa. (Uniprot ID: P24394) IL4R Tumor Antigens Datasheet 100 µg Inquiry
VAng-1617Lsx Biotinylated Human IL-4 R alpha Protein (Met 26-His 232) [Avi] [His] HEK293 Cells. Biotinylated Human IL-4 R alpha protein, Avi tag and His tag, expressed in human 293 cells. (Uniprot ID: NP_000409.1) IL4R Tumor Antigens Datasheet 25 µg Inquiry
VAng-1649Lsx Cynomolgus / Rhesus macaque IL-4 R alpha Protein (Met 26-Arg 232) [Fc] HEK293 Cells. Cynomolgus / Rhesus macaque IL-4 R alpha protein, Fc tag, expressed in human 293 cells. (Uniprot ID: G7Q0S7) IL4R Tumor Antigens Datasheet 50 µg Inquiry
VAng-1650Lsx Cynomolgus / Rhesus macaque IL-4 R alpha Protein (Met 26-Arg 232) [His] HEK293 Cells. Cynomolgus / Rhesus macaque IL-4 R alpha protein, His tag, expressed in human 293 cells. (Uniprot ID: G7Q0S7) IL4R Tumor Antigens Datasheet 50 µg Inquiry
VAng-1826Lsx Human IL-4 R alpha Protein (Met 26-His 232) [Fc] HEK293 Cells. Human IL-4 R alpha protein, Fc tag, expressed in human 293 cells. (Uniprot ID: P24394-1) IL4R Tumor Antigens Datasheet 100 µg Inquiry
VAng-1827Lsx Human IL-4 R alpha Protein (Met 26-His 232) [His] HEK293 Cells. Human IL-4 R alpha protein, His tag, expressed in human 293 cells. (Uniprot ID: NP_000409.1) IL4R Tumor Antigens Datasheet 50 µg Inquiry
VAng-1938Lsx Mouse IL-4 R alpha Protein (Ile 26-Arg 233) [Fc] HEK293 Cells. Mouse IL-4 R alpha protein, Fc tag, expressed in human 293 cells. (Uniprot ID: NP_001008700) IL4R Tumor Antigens Datasheet 100 µg Inquiry
VAng-1939Lsx Mouse IL-4 R alpha Protein (Ile 26-Arg 233) [His] HEK293 Cells. Mouse IL-4 R alpha protein, His tag, expressed in human 293 cells. (Uniprot ID: NP_001008700) IL4R Tumor Antigens Datasheet 100 µg Inquiry

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