ITGA4
ITGA4 belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGA4 gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-Cr3762 | Recombinant ITGA4 Protein (Met1-Thr977) [His] | Mammalian cells | Recombinant ITGA4 Protein (Met1-Thr977) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 150-170 kDa. (Uniprot ID: P13612) | ITGA4 | Tumor Antigens |  |
100 µg | Inquiry |
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