LRP5
LRP5 (LDL Receptor Related Protein 5) is a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
---|---|---|---|---|---|---|---|---|
VAng-1900Lsx | Human LRP5 Protein (Glu 644-Gln 1263) [Fc] | HEK293 Cells. | Human LRP5 protein, Mouse IgG2a Fc Tag, expressed in human 293 cells. (Uniprot ID: O75197-1) | LRP5 | Tumor Antigens | ![]() |
100 µg | Inquiry |
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