Oncostatin M
OSM (Oncostatin M) is a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Diseases associated with OSM include Kaposi Sarcoma and Indolent Myeloma.| CAT | Product Name | Source | Product Overview | Target | Type | Datasheet | Size | Price |
|---|---|---|---|---|---|---|---|---|
| VAng-2622Lsx | Human OSM Protein (Ala 26-Arg 252) | HEK293 cells | Human Oncostatin M protein, was expressed in human 293 cells. (Uniprot ID: NP_065391.1) | Oncostatin M | Tumor Antigens |  |
50 µg | Inquiry |
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