SIGLEC5

SIGLEC5 (Sialic Acid Binding Ig Like Lectin 5) is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

CAT Product Name Source Product Overview Target Type Datasheet Size Price
VAng-2721Lsx Human CD170 Protein (Glu 17-Thr 434) [Fc] HEK293 cells Human Siglec-5 (CD170) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: AAH29896) SIGLEC5 Tumor Antigens Datasheet 100 µg Inquiry

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