CA9

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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-SB-LX0037 Anti-CA9 (3E4) h(CD28-CD3ζ) CAR, pSBCAR1 Human 3E4 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0038 Anti-CA9 (21C7) h(CD28-CD3ζ) CAR, pSBCAR1 Human 21C7 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0039 Anti-CA9 (M75) h(CD28-CD3ζ) CAR, pSBCAR1 Human M75 Mouse scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0040 Anti-CA9 (Girentuximab) h(CD28-CD3ζ) CAR, pSBCAR1 Human Girentuximab Mouse scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0041 Anti-CA9 (G37) h(CD28-CD3ζ) CAR, pSBCAR1 Human G37 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0622-ZP3218 Anti-CA9 h(VHH1-VHH2-CD28-CD3ζ) Biepitopic CAR, pCDCAR1 Human VHH1-VHH2-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-0622-ZP3390 Anti-CA9 h(VHH1-VHH2-4-1BB-CD3ζ) Biepitopic CAR, pCDCAR1 VHH1-VHH2-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
XS-0722-YF4 TS-Fluc Anti-Human CA9 scFv (CB515) CD28-CD3ζ CAR, pCDCAR1 Human CB515 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF64 TS-Fluc Anti-Human CA9 scFv (CB515) 4-1BB-CD3ζ CAR, pCDCAR1 Human CB515 Mouse 7H-YB-Fluc-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF124 TS-Fluc Anti-Human CA9 scFv (CB515) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human CB515 Mouse 7H-YB-Fluc-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF184 TS-IL15 SA Anti-Human CA9 scFv (CB515) CD28-CD3ζ CAR, pCDCAR1 Human CB515 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF244 TS-IL15 SA Anti-Human CA9 scFv (CB515) 4-1BB-CD3ζ CAR, pCDCAR1 Human CB515 Mouse 7H-YB-IL15 SA-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF304 TS-IL15 SA Anti-Human CA9 scFv (CB515) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human CB515 Mouse 7H-YB-IL15 SA-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF424 TS-NKG2DL Anti-hCD3 and Anti-Human CA9 scFv (CB515) 4-1BB-CD3ζ CAR, pCDCAR1 Human CB515 Mouse 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-YF484 TS-NKG2DL Anti-hCD3 and Anti-Human CA9 scFv (CB515) CD28-4-1BB-CD3ζ CAR, pCDCAR1 Human CB515 Mouse 7H-YB-NKG2DL Anti-hCD3 and (OKT3 scFv-NKG2D ECD)-EF1a-scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0823-LX3 Anti-hCA9 (H1L1) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human H1L1 Adenoviral vectors   Add to Cart   Datasheet
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