CD40

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP7136 Anti-CD40 (21.4.1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 21.4.1 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7137 Anti-CD40 (21.4.1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 21.4.1 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7138 Anti-CD40 (FGK45.5) m(CD28-CD3ζ) CAR, pCDCAR1 Mouse FGK45.5 Rat scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7139 Anti-CD40 (FGK45.5) h(4-1BB-CD3ζ) CAR, pCDCAR1 Mouse FGK45.5 Rat scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7142 Anti-CD40 (MAB89) h(CD28-CD3ζ) CAR, pCDCAR1 Human MAB89 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7143 Anti-CD40 (MAB89) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human MAB89 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7144 Anti-CD40 (23.28.1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 23.28.1 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7145 Anti-CD40 (23.28.1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 23.28.1 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7146 Anti-CD40 (23.5.1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 23.5.1 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7147 Anti-CD40 (23.5.1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 23.5.1 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7198 Anti-CD40 (5C3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5C3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7199 Anti-CD40 (5C3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 5C3 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7200 Anti-CD40 (4G3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4G3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7201 Anti-CD40 (4G3) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 4G3 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7202 Anti-CD40 (4G15) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4G15 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7203 Anti-CD40 (4G15) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 4G15 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7204 Anti-CD40 (4F11) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4F11 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7205 Anti-CD40 (4F11) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 4F11 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7206 Anti-CD40 (3G10) h(CD28-CD3ζ) CAR, pCDCAR1 Human 3G10 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP7207 Anti-CD40 (3G10) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 3G10 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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