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cMet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP018 Anti-cMet (ZP6-14) h(CD28-CD3ζ) CAR, pCDCAR1 Human ZP6-14 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP044 Anti-cMet (ZP6-14) h(41BB-CD3ζ) CAR, pCDCAR1 Human ZP6-14 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4445 Anti-cMet (ABT-700) h(CD28-CD3ζ) CAR, pCDCAR1 Human ABT-700 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4446 Anti-cMet (38H10) h(CD28-CD3ζ) CAR, pCDCAR1 Human 38H10 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4447 Anti-cMet (OptDl 1) h(CD28-CD3ζ) CAR, pCDCAR1 Human OptDl 1 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4448 Anti-cMet (XP7-105) h(CD28-CD3ζ) CAR, pCDCAR1 Human XP7-105 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4449 Anti-cMet (XP7-106) h(CD28-CD3ζ) CAR, pCDCAR1 Human XP7-106 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4450 Anti-cMet (XP7-107) h(CD28-CD3ζ) CAR, pCDCAR1 Human XP7-107 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4451 Anti-cMet (XP7-108) h(CD28-CD3ζ) CAR, pCDCAR1 Human XP7-108 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4452 Anti-cMet (XP7-109) h(CD28-CD3ζ) CAR, pCDCAR1 Human XP7-109 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4453 Anti-cMet (P3D12) h(CD28-CD3ζ) CAR, pCDCAR1 Human P3D12 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4454 Anti-cMet (XP7-110) h(CD28-CD3ζ) CAR, pCDCAR1 Human XP7-110 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4455 Anti-cMet (PGIA-3-A9) h(CD28-CD3ζ) CAR, pCDCAR1 Human PGIA-3-A9 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4456 Anti-cMet (XP7-111) h(CD28-CD3ζ) CAR, pCDCAR1 Human XP7-111 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4457 Anti-cMet (PGIA-1-A1) h(CD28-CD3ζ) CAR, pCDCAR1 Human PGIA-1-A1 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4458 Anti-cMet (XP7-112) h(CD28-CD3ζ) CAR, pCDCAR1 Human XP7-112 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-ZP4656 Anti-cMet (ABT-700) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human ABT-700 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0323-LX298 Anti-cMet VHH(X3XH298) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH298 VHH-CD28-41BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX667 Anti-cMet VHH(X3XH298) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Vector Human X3XH298 VHH-ICOS-4-1BB-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0323-LX1036 Anti-cMet VHH(X3XH298) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Vector Human X3XH298 VHH-CD28-OX40-CD3ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
XS-0823-LX31 Anti-hcMet (KR10) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human KR10 Adenoviral vectors   Add to Cart   Datasheet
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