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Chondroitin sulfate proteoglycan 4 (CSPG4), also known as melanoma-associated chondroitin sulfate proteoglycan (MCSP), neuron-glial antigen 2 (NG2), HMW-MAA, MEL-CSPG or MSK16G, is a chondroitin sulfate proteoglycan and encoded by the CSPG4 gene. CSPG4 is essential to the growth of melanoma tumor through its modulation of integrin function and enhanced growth factor receptor regulated pathways. Therefore, CSPG4 is related to melanoma.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| CAR-LC134 | Anti-CSPG4 (763.74) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 763.74 | Mouse | scFv-CD28-CD3ζ | Retroviral | T cell | ||
| CAR-MZ116 | Anti-CSPG4 (TP41.2) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | TP41.2 | Mouse | scFv-CD28-CD3ζ | Retroviral | T cell | ||
| CAR-MZ117 | Anti-CSPG4 (149.53) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 149.53 | Mouse | scFv-CD28-CD3ζ | Retroviral | T cell | ||
| CAR-MZ118 | Anti-CSPG4 (G71.1) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | G71.1 | Mouse | scFv-CD28-CD3ζ | Retroviral | T cell | ||
| CAR-MZ198 | Anti-CSPG4 (763.74) h(CD3ζ) CAR, pCDCAR1 | Human | 763.74 | Mouse | scFv-CD3ζ | Retroviral | T cell | ||
| CAR-MZ200 | Anti-CSPG4 (763.74) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | 763.74 | Mouse | scFv-41BB-CD3ζ | Retroviral | T cell | ||
| XS-0822-YF299 | Anti-Human CSPG4 (XW-299) h(41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-299 | Mouse | scFv-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF1219 | Anti-Human CSPG4 (XW-299) h(CD28-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-299 | Mouse | scFv-CD28-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0822-YF2139 | Anti-Human CSPG4 (XW-299) h(CD28-41BB-CD3ζ) CAR IVT Plasmid, pCARIVT | Human | XW-299 | Mouse | scFv-CD28-41BB-CD3ζ | In Vitro Transcription (IVT) Vector | |||
| XS-0922-ZP1310 | Anti-CSPG4 (763.74) h(4-1BB-CD3ζ) CAR, pCDCAR1 | Human | 763.74 | Mouse | scFv-4-1BB-CD3ζ | Lentiviral vector | T cell | ||
| XS-1122-YF299 | Anti-CSPG4 KIR CAR (scFv-KIR2DS2-DAP12, XW-299), pCDCAR1 | Human | XW-299 | Mouse | scFv-KIR2DS2 TM&ICD-2A-DAP12 | Lentiviral vector | T Cell | ||
| XS-1122-YF1219 | Anti-CSPG4 TCR-ABR (scFv-TCRα, XW-299) CAR Plasmid, pCDCAR1 | Human | XW-299 | Mouse | scFv-TCRα | Lentiviral vector | T Cell | ||
| XS-1122-YF2139 | Anti-CSPG4 TCR-ABR (scFv-TCRβ, XW-299) CAR Plasmid, pCDCAR1 | Human | XW-299 | Mouse | scFv-TCRβ | Lentiviral vector | T Cell | ||
| XS-1122-YF3059 | Anti-CSPG4 TCR-ABR (scFv-CD3γ, XW-299) CAR Plasmid, pCDCAR1 | Human | XW-299 | Mouse | scFv-CD3γ | Lentiviral vector | T Cell | ||
| XS-1122-YF3979 | Anti-CSPG4 TCR-ABR (scFv-CD3δ, XW-299) CAR Plasmid, pCDCAR1 | Human | XW-299 | Mouse | scFv-CD3δ | Lentiviral vector | T Cell | ||
| XS-1122-YF4899 | Anti-CSPG4 TCR-ABR (scFv-CD3ε, XW-299) CAR Plasmid, pCDCAR1 | Human | XW-299 | Mouse | scFv-CD3ε | Lentiviral vector | T Cell | ||
| XS-1122-YF5819 | Anti-CSPG4 (XW-299) h(CD28-CD3ζ) CAR, pAAV | Human | XW-299 | Mouse | scFv-CD28-CD3ζ | Adeno-associated viral (AAV) vector | T Cell | ||
| XS-0123-ZP672 | Anti-CSPG4 (763.74) h(scFv-CD3ε) TRuC, pCDTRC1 | Human | 763.74 | Mouse | scFv-CD3ε | Lentiviral vector | T cell | ||
| XS-0323-ZP672 | Anti-CSPG4 (763.74 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | 763.74 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0923-LX68 | Anti-hCSPG4 (CD28-41BB-CD3ζ) CAR-duplex CTLA4 pCDCAR1 Vector | Human | X9X-37 | scFv-CD28-41BB-CD3ζ-duplex CTLA4 | Lentiviral vector | T cell | CAR-T |
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CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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