EGFRvIII

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Epidermal growth factor receptor variant III (EGFRvIII) is an extracellular domain mutation of epidermal growth factor receptor (EGFR), which leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRvIII is considerably expressed in glioblastoma multiforme (GBM), which results in overexpression of the transmembrane tyrosine kinase receptor (EGFR). Therefore, EGFRvIII is related to glioblastoma multiforme (GBM).

Associated Disease
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-MV-01LX040 Anti-EGFRvIII (3C10) h(CD28-CD3ζ) CAR, pMMLV Human 3C10 Mouse scFv-CD28-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX041 Anti-EGFRvIII (mab108) h(CD28-CD3ζ) CAR, pMMLV Human mab108 Mouse scFv-CD28-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX042 Anti-EGFRvIII (mab139) h(CD28-CD3ζ) CAR, pMMLV Human mab139 Mouse scFv-CD28-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX245 Anti-EGFRvIII (clone139) h(CD28-CD3ζ) CAR, pMMLV Human clone139 Humanized scFv-CD28-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX285 Anti-EGFRvIII (3C10) h(41BB-CD3ζ) CAR, pMMLV Human 3C10 Mouse scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX286 Anti-EGFRvIII (mab108) h(41BB-CD3ζ) CAR, pMMLV Human mab108 Mouse scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX287 Anti-EGFRvIII (mab139) h(41BB-CD3ζ) CAR, pMMLV Human mab139 Mouse scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-MV-01LX490 Anti-EGFRvIII (clone139) h(41BB-CD3ζ) CAR, pMMLV Human clone139 Humanized scFv-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
CAR-SB-02LX038 Anti-EGFRvIII (3C10) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 Human 3C10 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX039 Anti-EGFRvIII (mab108) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 Human mab108 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX040 Anti-EGFRvIII (mab139) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 Human mab139 Mouse scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX242 Anti-EGFRvIII (clone139) h(CD28-41BB-CD3ζ) CAR, pSBCAR1 Human clone139 Humanized scFv-CD28-41BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX280 Anti-EGFRvIII (3C10) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human 3C10 Mouse scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX281 Anti-EGFRvIII (mab108) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human mab108 Mouse scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX282 Anti-EGFRvIII (mab139) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human mab139 Mouse scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX484 Anti-EGFRvIII (clone139) h(CD28-OX40-CD3ζ) CAR, pSBCAR1 Human clone139 Humanized scFv-CD28-OX40-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX522 Anti-EGFRvIII (3C10) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human 3C10 Mouse scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX523 Anti-EGFRvIII (mab108) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human mab108 Mouse scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX524 Anti-EGFRvIII (mab139) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human mab139 Mouse scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-02LX726 Anti-EGFRvIII (clone139) h(ICOS-4-1BB-CD3ζ) CAR, pSBCAR1 Human clone139 Humanized scFv-ICOS-4-1BB-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
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