FOLH1

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This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-0722-LX344 Anti-FOLH1 (X7X136) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X136 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX345 Anti-FOLH1 (X7X137) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X137 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX346 Anti-FOLH1 (X7X138) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X138 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX347 Anti-FOLH1 (X7X139) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X139 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX348 Anti-FOLH1 (X7X140) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X140 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX349 Anti-FOLH1 (X7X141) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X141 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX350 Anti-FOLH1 (X7X142) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X142 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX351 Anti-FOLH1 (X7X143) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 human X7X143 human scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX535 Anti-FOLH1 (X7X119) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X119 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX536 Anti-FOLH1 (X7X120) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X120 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX537 Anti-FOLH1 (X7X121) h(ICOS-4-1BB-CD3ζ) CAR, pCDCAR1 human X7X121 Humanized scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0722-LX721 Anti-FOLH1 (X7X97) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X97 Humanized scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX722 Anti-FOLH1 (X7X98) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X98 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX723 Anti-FOLH1 (X7X99) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X99 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX724 Anti-FOLH1 (X7X100) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X100 Mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX725 Anti-FOLH1 (X7X101) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X101 Humanized scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX726 Anti-FOLH1 (X7X102) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X102 Humanized scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX773 Anti-FOLH1 (X7X149) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X149 mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX774 Anti-FOLH1 (X7X150) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X150 mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
XS-0722-LX775 Anti-FOLH1 (X7X151) h(CD28-41BB-CD3ζ) CAR, pMMLV human X7X151 mouse scFv-CD28-41BB-CD3ζ Recombinant Moloney murine leukemia virus (MMLV) retroviral vector T cell   Add to Cart   Datasheet
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