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GCN4

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

General Control Protein GCN4, is a transcription factor for over 30 genes necessary for amino acid or purine biosynthesis in the case of amino acid or purine starvation. As a transcription factor located in the nucleus, GCN4 regulates many genes connected to purine biosynthesis, autophagy, multiple stress responses, glycogen homeostasis, and organelle biosynthesis. A specific antibody conjugated to GCN4 peptide can be used to redirect the activity of the CAR-T cells to antigen expressing cancer cells.

GCN4 Associated Disease
  • CAR Vector Products

  • CAR Cell Products

  • CAR Viral Particles

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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-LC281 Anti-GCN4 (X8LX1) h(41BB-CD3ζ, GCN4 (X8LX1)) Conditional CAR, pCDCAR1 Human X8LX1 Mouse scFv-41BB-CD3ζ Lentiviral T cell   Add to Cart   Datasheet
XS-0922-LX10 Anti-GCN4 (X9X10) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X9X10 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-LX11 Anti-GCN4 (X9X11) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Human X9X11 Mouse scFv-CD28-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-LX209 Anti-GCN4 (X9X10) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X9X10 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-LX210 Anti-GCN4 (X9X11) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 Human X9X11 Mouse scFv-CD28-OX40-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-LX408 Anti-GCN4 (X9X10) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X9X10 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-LX409 Anti-GCN4 (X9X11) h(ICOS-41BB-CD3ζ) CAR, pCDCAR1 Human X9X11 Mouse scFv-ICOS-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-LX607 Anti-GCN4 (X9X10) Negative Control CAR, pCDCAR1 Human X9X10 Mouse scFv-CD28/CD8TM Lentiviral vector T cell   Add to Cart   Datasheet
XS-0922-LX608 Anti-GCN4 (X9X11) Negative Control CAR, pCDCAR1 Human X9X11 Mouse scFv-CD28/CD8TM Lentiviral vector T cell   Add to Cart   Datasheet
XS-0823-LX50 Anti-hGCN4 (mabb) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human mabb Adenoviral vectors   Add to Cart   Datasheet
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