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GPC3

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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YF066 Anti-GPC3 (CBL-YF017) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF017 Humanized scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF067 Anti-GPC3 (CBL-YF017) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF017 Humanized scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF161 Anti-GPC3 (CBL-YF051) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBL-YF051 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YF162 Anti-GPC3 (CBL-YF051) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBL-YF051 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP126 Anti-GPC3 (hu9F2) h(CD28-CD3ζ) CAR, pCDCAR1 Human hu9F2 Humanized scFv-CD28-CD3ζ Lentiviral vector NK cell   Add to Cart   Datasheet
CAR-ZP127 Anti-GPC3 (hu9F2) h(41BB-CD3ζ) CAR, pCDCAR1 Human hu9F2 Humanized scFv-4-1BB-CD3ζ Lentiviral vector NK cell   Add to Cart   Datasheet
CAR-ZP200 Anti-GPC3 (1G12) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1G12 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP201 Anti-GPC3 (1G12) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1G12 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP202 Anti-GPC3 (GPC3A-37) h(CD28-CD3ζ) CAR, pCDCAR1 Human GPC3A-37 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP203 Anti-GPC3 (GPC3A-37) h(41BB-CD3ζ) CAR, pCDCAR1 Human GPC3A-37 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-M0158-YC Anti-GPC3 (CBYCD-474) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human CBYCD-474 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-M0569-YC Anti-GPC3 (CBYCD-474) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human CBYCD-474 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-SB-LX0269 Anti-GPC3 (15G1) h(CD28-CD3ζ) CAR, pSBCAR1 Human 15G1 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0270 Anti-GPC3 (7H1) h(CD28-CD3ζ) CAR, pSBCAR1 Human 7H1 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0271 Anti-GPC3 (2G9) h(CD28-CD3ζ) CAR, pSBCAR1 Human 2G9 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0272 Anti-GPC3 (4G5) h(CD28-CD3ζ) CAR, pSBCAR1 Human 4G5 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0273 Anti-GPC3 (3D8) h(CD28-CD3ζ) CAR, pSBCAR1 Human 3D8 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0274 Anti-GPC3 (3E11) h(CD28-CD3ζ) CAR, pSBCAR1 Human 3E11 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
CAR-SB-LX0275 Anti-GPC3 (2E10) h(CD28-CD3ζ) CAR, pSBCAR1 Human 2E10 Human scFv-CD28-CD3ζ Sleeping Beauty (SB) transposon T cell   Add to Cart   Datasheet
XS-0823-LX63 Anti-hGPC3 (Ab) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector Human Ab Adenoviral vectors   Add to Cart   Datasheet
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